Inflammatory Bowel Disease

Discussing the latest advances in Crohn’s disease and ulcerative colitis

Feb 10, 2017

FDA Approves Biosimilar to Humira

By Kanaaz Pereira @kanaazpe
The FDA recently approved a biosimilar (trade name, Amjevita) to Humira (adalimumab). A biosimilar is a biological product that is highly similar to the originator drug, and has no clinical differences in terms of safety and effectiveness. Dr. Edward Loftus , M.D., talks about the potential of this drug to offer patients with chronic inflammatory diseases such [...]
May 11, 2016

CCFA to Study Impact of Specific Diets on Crohn's Disease

By Kanaaz Pereira @kanaazpe
One of the first questions that people diagnosed with inflammatory bowel disease (IBD) have is, "What can I eat, and will changing my diet help with the symptoms or even cure my disease?"  The Crohn’s & Colitis Foundation of America (CCFA) has been given $2.5 million to investigate the value of a carbohydrate-rich [...]
May 6, 2016

FDA Approves of Biosimilar to Infliximab

By Kanaaz Pereira @kanaazpe
The FDA recently approved of a biosimilar (CT-P13) to infliximab, which is used for treating IBD patients, as well as patients suffering from rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, and plaque psoriasis. The new drug would be the first biosimilar monoclonal antibody approved in the United States. Dr. Edward Loftus, [...]
May 6, 2016

Can Oral Contraceptives Worsen Crohn's Disease?

By Kanaaz Pereira @kanaazpe
A new study, published in Gastroenterology, suggests that long-term use of combination oral contraceptives may increase the risk for surgery among women with established Crohn’s disease. The research team evaluated the association between oral contraceptives and risk for Crohn’s disease complications, including need for surgery and steroid use. They found [...]
May 3, 2016

Vedolizumab Safe for Inflammatory Bowel Disease

By Kanaaz Pereira @kanaazpe
Vedolizumab (proposed trade name Entyvio), was developed as a treatment for patients with moderate to severe ulcerative colitis (UC) or Crohn's disease (CD), who have failed at least one conventional therapy, including tumor necrosis factor (TNF) antagonists. Dr. Edward Loftus, M.D., reviews a recent study published in the journal Gut, [...]
Apr 19, 2016

IBD or IBS - That is the Question

By Kanaaz Pereira @kanaazpe
Many people are confused between two distinct gastrointestinal disorders: inflammatory bowel disease (IBD), and irritable bowel syndrome (IBS). Dr. Jean Fox, M.D., gives us a primer on the key differences, and similarities, between IBD and IBS. For more information about IBD and, visit Dr. Fox is a gastroenterologist at [...]
Apr 6, 2016

Can You Teach a Teen New Tricks?

By Kanaaz Pereira @kanaazpe
These days, everyone seems to have a coach. Here, Dr. Jeanne Tung, M.D., talks about problem solving coaching by telephone for teenagers with inflammatory bowel disease (IBD). We know that successfully taking medications for IBD is critical in inducing and maintaining remission. However, studies have shown that many teenagers [...]
Mar 26, 2016

Biologic Drugs – Are They Safe to Use During Pregnancy?

By Kanaaz Pereira @kanaazpe
One of the major medical therapies used to treat chronic inflammatory conditions such as Crohn's disease, ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, or psoriasis are anti-tumor necrosis factor (anti-TNF) agents. These include, but are not limited to drugs like Remicade, Simponi, Humira and Cimzia. Women who are pregnant, and taking these [...]
Mar 24, 2016

The New Birth Trend That’s All About Bacteria

By Kanaaz Pereira @kanaazpe
It may sound strange, but some women who give birth by caesarean section (C-section) are covering their newborn in fluid swabbed from their vagina! A baby born vaginally is exposed to a plethora of different bacteria as it comes down the birth canal; these bacteria set up the child’s microbiome, (bacteria [...]
Mar 5, 2016

Lifestyle and Diet in Inflammatory Bowel Disease

By Kanaaz Pereira @kanaazpe
Note: This post was originally published on Mayo Clinic News Network  Inflammatory bowel disease (IBD), which consists of Crohn’s disease and ulcerative colitis, can be a frustrating diagnosis to deal with. In general, there is no clear evidence that one trigger alone causes problems. Therefore, there is no particular food, diet [...]
Feb 29, 2016

Another Reason for Teens to Eat Their Vegetables

By Kanaaz Pereira @kanaazpe
Both Crohn’s disease (CD) and ulcerative colitis (UC) present day-to-day as well as long-term challenges for the adolescent patient. Based upon a study, published in the journal Inflammatory Bowel Diseases, Dr. Laura Raffals offers insights into the association between teenagers’ diet and the risk of developing IBD. Researchers categorized [...]
Feb 5, 2016

Are Fecal Transplants Effective in Children with IBD?

By Kanaaz Pereira @kanaazpe
Clostridium difficile infection (CDI) is the leading cause of nosocomial diarrhea and is increasing in prevalence both in adult and paediatric populations. Moreover, those with inflammatory bowel disease (IBD) are at increased risk of CDI. Fecal microbiota transplantation (FMT) is an effective treatment for recurrent CDI, but little data is available regarding [...]
Jan 27, 2016

Higher Risk for Pneumococcal Disease in IBD Patients

By Kanaaz Pereira @kanaazpe
Mayo Clinic gastroenterologist, Dr. William Tremaine discusses a recent study published in The American Journal of Gastroenterology, that aimed to determine the risk of pneumococcal disease in patients with inflammatory bowel disease (IBD), compared with the general population, and how IBD medications may affect this risk, or whether the risk varies before or [...]
Dec 29, 2015

Specific Carbohydrate Diet for Pediatric IBD

By Kanaaz Pereira @kanaazpe
Dietary intervention such as the specific carbohydrate diet (SCD), initially used to treat celiac disease, has been effective in patients with inflammatory bowel disease (IBD) as well. Dr. Jeanne Tung, M.D., discusses a study, published in the journal Nutrition, where pediatric gastroenterologists at Seattle Children's Hospital looked back at their [...]
Dec 20, 2015

Pregnancy Concerns in Women With IBD

By Kanaaz Pereira @kanaazpe
Women with inflammatory bowel disease (IBD) are at increased risk for adverse birth outcomes such as preterm delivery and small for gestational age (SGA) infants, and most recognized cases have underlying placental causes. Dr. Sunanda Kane, M.D., discusses a study, published in Annals of Gastroenterology that examined whether women with IBD [...]
Dec 13, 2015

New Gene Variants May Contribute to Very Early Onset IBD

By Kanaaz Pereira @kanaazpe
Major advances in understanding the genetic contribution to the development of inflammatory bowel diseases (IBD) have been achieved in the last decade. However, these studies were performed primarily in adults and in children 10 years of age and older, and did not include children with very early-onset IBD (VEO-IBD), diagnosed at younger [...]
Dec 4, 2015

Faecal Testing and IBD

By Kanaaz Pereira @kanaazpe
Inflammatory bowel disease (IBD), mainly consisting of Crohn’s disease and ulcerative colitis, are lifelong intestinal disorders, and disease flares are often unpredictable and significantly affect the patient’s quality of life. Sunanda Kane, M.D., discusses stool tests for pediatric and adult patients with inflammatory bowel disease, focusing  on two proteins that may [...]
Dec 3, 2015

Symptoms and Diagnosis of IBD

By Kanaaz Pereira @kanaazpe
How is inflammatory bowel disease (IBD) diagnosed? What are the symptoms? William Faubion, M.D., discusses these questions. For more information about IBD, visit Dr. Faubion is a gastroenterologist at Mayo Clinic specializing in pediatric and adult inflammatory bowel disease (IBD).
Dec 1, 2015

CCFA Awareness Week: Dec.1-7, 2015

By Kanaaz Pereira @kanaazpe
Living with inflammatory bowel disease (IBD) can be difficult, but the right resources and support can make day to day living much easier. The Crohn's & Colitis Foundation of America (CCFA) is a non-profit, volunteer-driven organization dedicated to finding the cures for Crohn's Disease and ulcerative colitis. In an effort [...]
Nov 21, 2015

Interval Colorectal Cancer Low with Surveillance Colonoscopy

By Kanaaz Pereira @kanaazpe
Surveillance is recommended for patients with chronic inflammatory bowel disease (IBD), as they have an increased risk of colorectal cancer (CRC). According to recent study data, published in Clinical Gastroenterology and Hepatology, the incidence of interval colorectal cancers, (cancers occurring between scheduled surveillance colonoscopies), is low in patients undergoing regular surveillance colonoscopy. Dr. John [...]
Nov 20, 2015

Insight into Endoscopic Balloon Dilatation for Crohn's Disease

By Kanaaz Pereira @kanaazpe
Endoscopic balloon dilatation (EBD) is a recognized treatment for symptomatic Crohn's strictures. Dr. Kenneth Schroeder M.D., talks about a recent study, published in Alimentary Pharmacology and Therapeutics, that examines the efficacy, as well as complication rates for EBD. The role of EBD in the management of Crohn's strictures may need to [...]
Nov 9, 2015

Highlights of ACG's Annual Scientific Meeting 2015

By Kanaaz Pereira @kanaazpe
For five days, from October 16 to October 21, 2015, renowned experts in the field of gastroenterology offered clinical insights and real-world perspectives at the American College of Gastroenterology's Annual Scientific Meeting in Hawaii. Dr. Sunanda Kane, M.D., summarizes some of the bigger studies that were presented at the meeting, including key research done [...]
Oct 29, 2015

Relapse Rates High in IBD Patients Who Stop Treatment

By Kanaaz Pereira @kanaazpe
Inflammatory bowel diseases (IBD), such as ulcerative colitis and Crohn’s disease, are chronic disorders of the gastrointestinal tract which require long term treatment to achieve remission, and to prevent relapses. While current therapies are effective, many concerns exist regarding their long term use. Recently, a new area of research has emerged, namely, the [...]
Oct 28, 2015

‘Creeping Fat’ May Contribute to IBD

By Kanaaz Pereira @kanaazpe
According to new research data, published in Cellular and Molecular Gastroenterology and Hepatology, intra-abdominal fat cells may play a role in the pathophysiology of inflammatory bowel disease. Dr. David Bruining, M.D., explains the study. Fat accumulation surrounding the inflamed intestine, (also known as 'creeping fat' or mesenteric fat), during Crohn’s disease represents [...]
Oct 13, 2015

C-Section Delivery Not a Risk Factor for IBD

By Kanaaz Pereira @kanaazpe
Cesarean section, also known as C-section,  versus vaginal delivery has been explored as a risk factor for developing inflammatory bowel disease (IBD). During birth, bacteria from the mother and the surrounding environment colonize the infant's gut, and during C-section delivery this direct contact is absent. Dr. Sunanda Kane, M.D., discusses the most recent [...]
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