Inflammatory Bowel Disease

Discussing the latest advances in Crohn’s disease and ulcerative colitis

January 23rd, 2015 · Leave a Comment

Stay Up-To-Date on IBD Research

By Margaret Shepard

Are you wondering how the latest research in inflammatory bowel disease might impact your treatment? Stay up-to-date and hear from Mayo Clinic doctors on how current research will impact the diagnoses and treatment your IBD by watching the IBD YouTube playlist.

For more information about IBD, visit mayoclinic.org/IBD.

Tags: Crohn's disease, IBD, ulcerative colitis

January 16th, 2015 · Leave a Comment

IBD and Pneumonia

By Margaret Shepard

Edward Loftus Jr., M.D., discusses a study published in American Journal of Gastroenterology that found patients with inflammatory bowel disease were at an increased risk of pneumonia. In addition, Dr. Loftus also discusses the patient implications brought about by the study findings.

For more information about IBD, visit mayoclinic.org/ibd.

Edward Loftus Jr., M.D., is a gastroenterologist at Mayo Clinic specializing in the care and evaluation of patients with IBD.

Tags: American Journal of Gastroenterology, Edward Loftus, IBD, pneumonia

January 9th, 2015 · Leave a Comment

IBD and Impact on School Experience

By Margaret Shepard

As school starts back up after winter break, Jeanne Tung, M.D., lists helpful tips for children to minimize their condition's impact on their school experience.

For more information about IBD, visit mayoclinic.org/ibd.

Dr. Tung is a a pediatric gastroenterologist at Mayo Clinic specializing in the care and evaluation of patients with inflammatory bowel disease (IBD).

Tags: IBD, Jeanne Tung, pediatric care, tips

January 2nd, 2015 · Leave a Comment

Crohn's Disease or Ulcerative Colitis?

By Margaret Shepard

Crohn's disease and ulcerative colitis are inflammatory bowel diseases that share many symptoms: stomach pain, cramping, the need to always be near a bathroom. The two conditions may seem similar, but in truth, they're quite different and require different treatments. And because they can often be tricky to tell apart, some patients suffer symptoms for years before they find relief.

For more information on IBD, visit mayoclinic.org/ibd.

Tags: Crohn's disease, IBD, ulcerative colitis

December 24th, 2014 · Leave a Comment

Therapeutic Drug Monitoring of Anti-TNF Therapy

By Margaret Shepard

Therapeutic drug monitoring is now extending to newer biologics, including TNF inhibitors such as infliximab, a chimeric monoclonal antibody, and adalimumab, a fully human monoclonal antibody. Although these drugs have improved outcomes for some refractory patients, they have been unsatisfactory for others.

Edward V. Loftus Jr., M.D., comments on the effectiveness of therapeutic drug monitoring in a recent Digestive Diseases Update.

For more information about IBD, visit mayoclinic.org/ibd.

Dr. Loftus is a gastroenterologist at Mayo Clinic.

Tags: Anti-TNF agents, drug therapy, Edward Loftus, IBD, therapeutic drug monitoring

December 18th, 2014 · Leave a Comment

Vedolizumab Is Better for Ulcerative Colitis Than Crohn's Disease

By Margaret Shepard

In December 2013, two Food and Drug Administration (FDA) advisory committees voted in favor of recommending vedolizumab for treatment of both types of inflammatory bowel disease.

A theoretical concern about vedolizumab is the risk of progressive multifocal leukoencephalopathy (PML), a potentially fatal brain infection associated with vedolizumab's parent molecule, natalizumab (Tysabri), which is approved for use in both multiple sclerosis and CD.

Edward V. Loftus Jr., M.D., a gastroenterologist at Mayo Clinic in Minnesota, points out that natalizumab affects adhesion molecules at the level of the blood-brain barrier system as well as in the gut. "The goal has always been to develop more gut-specific targets," he says.

Read more about vedolizumab in the Digestive Diseases update.

To learn more about IBD, visit mayoclinic.org/ibd.

Tags: clinical trials, Crohn's disease, Edward Loftus, IBD, ulcerative colitis, Vedolizumab

December 12th, 2014 · Leave a Comment

Small Bowel Imaging and Crohn's Disease

By Margaret Shepard

Advances in small bowel imaging over the past decade have transformed the diagnosis and management of inflammatory bowel disease. New modalities such as CT and MR enterography, CT and MR enteroclysis, capsule endoscopy (CE), and balloon-assisted endoscopy (BAE) have become essential for evaluating the extent and severity of Crohn's disease (CD) and monitoring intestinal response to treatment.

Read more about the advances in imaging the Digestive Diseases update.

For more information about inflammatory bowel disease, visit mayoclinic.org/IBD.

 

Tags: Crohn's disease, IBD, small bowel imaging

December 5th, 2014 · Leave a Comment

IBD Biobank

By Margaret Shepard

In 2013, Mayo Clinic instituted an inflammatory bowel disease (IBD) serum biobank involving Mayo campuses in Arizona, Florida and Minnesota and the Mayo Clinic Health System. The goal was to use serologic samples from patients with diagnosed ulcerative colitis (UC) or Crohn's disease (CD) to advance biomarker research that might one day improve diagnosis, prognosis and treatment of IBD.

A year after its inception, a serum biobank that unites research across Mayo Clinic is helping identify new serologic biomarkers in patients with Crohn's disease and advancing other IBD research. Read more about the biobank here.

For more information on IBD, visit mayoclinic.org/ibd.

Tags: biobank, Crohn's disease, IBD, ulcerative colitis

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