Inflammatory Bowel Disease

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August 7, 2015

Therapeutic Management of Children with Very Early-Onset Bowel Disease

By Kanaaz Pereira

Once a medical rarity in children, inflammatory bowel disease (IBD) is increasingly common in kids today. Patients who are diagnosed with this disease at a very young age, sometimes less than 6 years old, have what is known as very early-onset IBD (VEO-IBD). Mayo Clinic gastroenterologist, Michael Stephens M.D., discusses a study published in The Journal of Pediatrics, that evaluates the diagnosis, management and long-term outcomes of children with very early-onset IBD.

The study found that children with VEO-IBD can present unique challenges to physicians and health-care providers. It starts as a relatively mild disease, and tends to be isolated to the large intestine. Over time, however, it changes in behavior, becoming more severe, and involving other regions of the intestine.

VEO-IBD is appearing more frequently on physicians' radars, and it is important to recognize that children are not small adults. Many of the children have definable problems with their immune system, and collaborating with good immunologists, as well as advanced genetic testing can facilitate more customized and enhanced treatment.

Read the full story online here.

For more information about IBD, visit

Dr. Stephens is a gastroenterologist at Mayo Clinic.

Tags: genetic testing, IBD, immune system, Michael Stephens, Study Findings, The Journal of Pediatrics, VEO-IBD

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