Inflammatory Bowel Disease

Discussing the latest advances in Crohn’s disease and ulcerative colitis

Share this:
July 17, 2014

Treat-to-Target Therapy in Crohn’s Disease Patients

By Margaret Shepard, Communications Specialist

Do have Crohn's disease and are wondering if your treatment therapy is working? Sunanda Kane, M.D., discusses a recently published article in Clinical Gastroenterology and Hepatology about treating to target Crohn’s disease.


The researchers, from the University of California at San Diego, previously published a paper on treating-to-target ulcerative colitis. Treating for intestinal healing is the most effective way of getting patients in remission and feeling the best they possibly can.

What does this mean? A patient may be on a biologic, still have diarrhea, abdominal pain or unable to gain weight but feel well. It could be beneficial to look at the intestinal tissue with a scope to see if the therapy is doing the most it can for the patient. With all the biologics to treat Crohn's disease, it is possible to check blood levels and increase the dosage to target healing of the tissue. Any presence of inflammation or ulcers may contribute to continued symptoms. The goal should be treating to heal.

The expectation is that intestinal tissue can heal. While it may be uncomfortable to undergo colonoscopies, it's helpful in the short term and long term for treatment of the disease.

Read the full study online here.

For more information on IBD , visit

Dr. Kane is a gastroenterologist at Mayo Clinic.

Tags: Clinical Gastroenterology and Hepatology, Crohn's disease, Study Findings, Sunanda Kane

Hello , my 23year old son has crohns disease , he is starting to show memory loss , it is affect his work , soial life , lost, n not coping with disease , is memory loss sort term or will it get worse, who can we keep his brain working

Please login or register to post a reply.
Contact Us · Privacy Policy