Laura Raffals, M.D., discusses a recent study published in the Journal of Alimentary Pharmacology & Therapeutics that found smokers were much more likely to have aggressive disease behavior. The study, which came out of Spain, was the largest of its kind, having examined disease behavior and smoking status of over 3,000 patients with Crohn's disease.
Specifically, the patients who were smokers were more likely to:
- Have stricturing disease, or narrowing in their intestines
- Develop perianal disease in a shorter time-frame
- Require immunosuppressive treatments
Dr. Raffals is a gastroenterologist at Mayo Clinic specializing in the care and evaluation of patients with IBD.