Inflammatory Bowel Disease

Discussing the latest advances in Crohn’s disease and ulcerative colitis

Study Findings

May 6th, 2016

Can Oral Contraceptives Worsen Crohn’s Disease?

By Kanaaz Pereira kanaazpe

A new study, published in Gastroenterology, suggests that long-term use of combination oral contraceptives may increase the risk for surgery among women with established Crohn’s disease. The research team evaluated the association between oral contraceptives and risk for Crohn’s disease complications, including need for surgery and steroid use. They found that steroid use did not […]

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Tags: Crohn's disease, Gastroenterology, IBD, oral contraceptives, Sunanda Kane, surgery


May 3rd, 2016

Vedolizumab Safe for Inflammatory Bowel Disease

By Kanaaz Pereira kanaazpe

Vedolizumab (proposed trade name Entyvio), was developed as a treatment for patients with moderate to severe ulcerative colitis (UC) or Crohn’s disease (CD), who have failed at least one conventional therapy, including tumor necrosis factor (TNF) antagonists. Dr. Edward Loftus, M.D., reviews a recent study published in the journal Gut, in which researchers reported on […]

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Tags: Crohn's disease, Edward Loftus, Entyvio, GUT, IBD, monoclonal antibody, ulcerative colitis, Vedolizumab


April 6th, 2016

Can You Teach a Teen New Tricks?

By Kanaaz Pereira kanaazpe

These days, everyone seems to have a coach. Here, Dr. Jeanne Tung, M.D., talks about problem solving coaching by telephone for teenagers with inflammatory bowel disease (IBD). We know that successfully taking medications for IBD is critical in inducing and maintaining remission. However, studies have shown that many teenagers may not be following through with […]

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Tags: coaching, IBD, Inflammatory Bowel Diseases, Jeanne Tung, medication adherence, phone counseling, teenagers


March 26th, 2016

Biologic Drugs – Are They Safe to Use During Pregnancy?

By Kanaaz Pereira kanaazpe

One of the major medical therapies used to treat chronic inflammatory conditions such as Crohn’s disease, ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, or psoriasis are anti-tumor necrosis factor (anti-TNF) agents. These include, but are not limited to drugs like Remicade, Simponi, Humira and Cimzia. Women who are pregnant, and taking these medications are always concerned about […]

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Tags: Anti-TNF agents, Cimzia, Clinical Gastroenterology and Hepatology, Crohn's disease, Humira, IBD, pregnancy, psoriasis, Remicade, rheumatoid arthritis, Simponi, Sunanda Kane


March 24th, 2016

The New Birth Trend That’s All About Bacteria

By Kanaaz Pereira kanaazpe

It may sound strange, but some women who give birth by caesarean section (C-section) are covering their newborn in fluid swabbed from their vagina! A baby born vaginally is exposed to a plethora of different bacteria as it comes down the birth canal; these bacteria set up the child’s microbiome, (bacteria in human skin, guts, and […]

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Tags: bacteria, C-section, cesarean section, IBD, immune system, microbiome, Nature Medicine, Sunanda Kane


February 5th, 2016

Are Fecal Transplants Effective in Children with IBD?

By Kanaaz Pereira kanaazpe

Clostridium difficile infection (CDI) is the leading cause of nosocomial diarrhea and is increasing in prevalence both in adult and paediatric populations. Moreover, those with inflammatory bowel disease (IBD) are at increased risk of CDI. Fecal microbiota transplantation (FMT) is an effective treatment for recurrent CDI, but little data is available regarding the effectiveness and associated microbiome […]

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Tags: Alimentary Pharmacology & Therapeutics, Clostridium difficile infection (CDI), fecal microbiome, fecal transplant, IBD, Mark Bartlett


January 27th, 2016

Higher Risk for Pneumococcal Disease in IBD Patients

By Kanaaz Pereira kanaazpe

Mayo Clinic gastroenterologist, Dr. William Tremaine discusses a recent study published in The American Journal of Gastroenterology, that aimed to determine the risk of pneumococcal disease in patients with inflammatory bowel disease (IBD), compared with the general population, and how IBD medications may affect this risk, or whether the risk varies before or after IBD diagnosis. Researchers from […]

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Tags: American Journal of Gastroenterology, IBD, pneumococcal disease, vaccinations, William Tremaine


December 29th, 2015

Specific Carbohydrate Diet for Pediatric IBD

By Kanaaz Pereira kanaazpe

Dietary intervention such as the specific carbohydrate diet (SCD), initially used to treat celiac disease, has been effective in patients with inflammatory bowel disease (IBD) as well. Dr. Jeanne Tung, M.D., discusses a study, published in the journal Nutrition, where pediatric gastroenterologists at Seattle Children’s Hospital looked back at their patients who had tried the […]

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Tags: diet, fecal microbiome, IBD, Jeanne Tung, nutrition, Specific Carbohydrate Diet


December 20th, 2015

Pregnancy Concerns in Women With IBD

By Kanaaz Pereira kanaazpe

Women with inflammatory bowel disease (IBD) are at increased risk for adverse birth outcomes such as preterm delivery and small for gestational age (SGA) infants, and most recognized cases have underlying placental causes. Dr. Sunanda Kane, M.D., discusses a study, published in Annals of Gastroenterology that examined whether women with IBD have a higher rate of […]

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Tags: Annals of Gastroenterology, Crohn's disease, IBD, placental inflammation, pregnancy, Sunanda Kane, ulcerative colitis


December 13th, 2015

New Gene Variants May Contribute to Very Early Onset IBD

By Kanaaz Pereira kanaazpe

Major advances in understanding the genetic contribution to the development of inflammatory bowel diseases (IBD) have been achieved in the last decade. However, these studies were performed primarily in adults and in children 10 years of age and older, and did not include children with very early-onset IBD (VEO-IBD), diagnosed at younger than 5 years of age. […]

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Tags: Gastroenterology, genome-wide association studies, IBD, Konstantinos Papdakis, VEO-IBD


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